Human CASQ2 activation kit by CRISPRa

CAT#: GA100598

CASQ2 CRISPRa kit - CRISPR gene activation of human calsequestrin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CASQ2
• Locus ID: 845
• Kit Components:

  GA100598G1, CASQ2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100598G2, CASQ2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100598G3, CASQ2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001232
• Synonyms: PDIB2
• Summary: 'The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq, Jul 2008]'