Human RUNX1 activation kit by CRISPRa

CAT#: GA100605

RUNX1 CRISPRa kit - CRISPR gene activation of human RUNX family transcription factor 1

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Frequently bought together (1)
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    • 100 ul

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol RUNX1
Locus ID 861
Kit Components

GA100605G1, RUNX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100605G2, RUNX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100605G3, RUNX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001001890, NM_001122607, NM_001754
Synonyms AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB
Summary 'Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.