Human CCKAR activation kit by CRISPRa

CAT#: GA100621

CCKAR CRISPRa kit - CRISPR gene activation of human cholecystokinin A receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCKAR
• Locus ID: 886
• Kit Components:

  GA100621G1, CCKAR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100621G2, CCKAR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100621G3, CCKAR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000730
• Synonyms: CCK-A; CCK1-R; CCK1R; CCKRA
• Summary: 'This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008]'