Human SCARB1 activation kit by CRISPRa

CAT#: GA100671

SCARB1 CRISPRa kit - CRISPR gene activation of human scavenger receptor class B member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCARB1
• Locus ID: 949
• Kit Components:

  GA100671G1, SCARB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100671G2, SCARB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100671G3, SCARB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001082959, NM_005505, NM_001367981, NM_001367983, NM_001367986, NM_001367988, NR_160416, NR_160417, NR_160419, NR_160421, NM_001367982, NM_001367984, NM_001367985, NM_001367987, NM_001367989, NR_160418, NR_160420, NR_160422, NR_160423, NR_160424
• Synonyms: CD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1
• Summary: 'The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2019]'