Human CD47 activation kit by CRISPRa

CAT#: GA100683

CD47 CRISPRa kit - CRISPR gene activation of human CD47 molecule

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD47
• Locus ID: 961
• Kit Components:

  GA100683G1, CD47 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100683G2, CD47 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100683G3, CD47 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025079, NM_001025080, NM_001777, NM_198793
• Synonyms: IAP; MER6; OA3
• Summary: This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]