Human CD70 activation kit by CRISPRa

CAT#: GA100691

CD70 CRISPRa kit - CRISPR gene activation of human CD70 molecule

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD70
• Locus ID: 970
• Kit Components:

  GA100691G1, CD70 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100691G2, CD70 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100691G3, CD70 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252, NM_001330332
• Synonyms: CD27L; CD27LG; TNFSF7
• Summary: 'The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]'