Human CDK2 activation kit by CRISPRa

CAT#: GA100730

CDK2 CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDK2
• Locus ID: 1017
• Kit Components:

  GA100730G1, CDK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100730G2, CDK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100730G3, CDK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001290230, NM_001798, NM_052827, NM_001290230.2
• Synonyms: CDKN2; p33(CDK2)
• Summary: 'This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'