Human CEACAM5 activation kit by CRISPRa

CAT#: GA100756

CEACAM5 CRISPRa kit - CRISPR gene activation of human carcinoembryonic antigen related cell adhesion molecule 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEACAM5
• Locus ID: 1048
• Kit Components:

  GA100756G1, CEACAM5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100756G2, CEACAM5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100756G3, CEACAM5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291484, NM_001308398, NM_004363, NM_001291484.3
• Synonyms: CD66e; CEA
• Summary: 'This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]'