Human CEBPD activation kit by CRISPRa

CAT#: GA100759

CEBPD CRISPRa kit - CRISPR gene activation of human CCAAT enhancer binding protein delta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEBPD
• Locus ID: 1052
• Kit Components:

  GA100759G1, CEBPD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100759G2, CEBPD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100759G3, CEBPD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005195
• Synonyms: C/EBP-delta; CELF; CRP3; NF-IL6-beta
• Summary: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]