Human CEBPE activation kit by CRISPRa

CAT#: GA100760

CEBPE CRISPRa kit - CRISPR gene activation of human CCAAT enhancer binding protein epsilon

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEBPE
• Locus ID: 1053
• Kit Components:

  GA100760G1, CEBPE gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100760G2, CEBPE gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100760G3, CEBPE gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001805
• Synonyms: C/EBP-epsilon; CRP1
• Summary: 'The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]'