Human RCBTB2 activation kit by CRISPRa

CAT#: GA100784

RCBTB2 CRISPRa kit - CRISPR gene activation of human RCC1 and BTB domain containing protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RCBTB2
• Locus ID: 1102
• Kit Components:

  GA100784G1, RCBTB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100784G2, RCBTB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100784G3, RCBTB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001268, NM_001286830, NM_001286831, NM_001286832, NM_001352424, NM_001352425, NM_001352426, NM_001352427, NM_001352428, NM_001352429, NM_001352430, NM_001352431, NR_147985
• Synonyms: CHC1L; RLG
• Summary: 'This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]'