Human CHD2 activation kit by CRISPRa

CAT#: GA100788

CHD2 CRISPRa kit - CRISPR gene activation of human chromodomain helicase DNA binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHD2
• Locus ID: 1106
• Kit Components:

  GA100788G1, CHD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100788G2, CHD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100788G3, CHD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042572, NM_001271
• Synonyms: EEOC
• Summary: 'The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'