Human Chromogranin A (CHGA) activation kit by CRISPRa

CAT#: GA100794

CHGA CRISPRa kit - CRISPR gene activation of human chromogranin A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHGA
• Locus ID: 1113
• Kit Components:

  GA100794G1, Chromogranin A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100794G2, Chromogranin A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100794G3, Chromogranin A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001275, NM_001301690, NM_001301690.2
• Synonyms: CGA
• Summary: 'The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]'