Human LYST activation kit by CRISPRa

CAT#: GA100807

LYST CRISPRa kit - CRISPR gene activation of human lysosomal trafficking regulator

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LYST
• Locus ID: 1130
• Kit Components:

  GA100807G1, LYST gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100807G2, LYST gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100807G3, LYST gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000081, NM_001005736, NM_001301365, NR_102436
• Synonyms: CHS; CHS1
• Summary: This gene encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Mutations in this gene are associated with Chediak-Higashi syndrome, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants, though the full-length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2013]