Human Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) activation kit by CRISPRa

CAT#: GA100818

CHRNB2 CRISPRa kit - CRISPR gene activation of human cholinergic receptor nicotinic beta 2 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHRNB2
• Locus ID: 1141
• Kit Components:

  GA100818G1, Nicotinic Acetylcholine Receptor beta 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100818G2, Nicotinic Acetylcholine Receptor beta 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100818G3, Nicotinic Acetylcholine Receptor beta 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000748
• Synonyms: EFNL3; nAChRB2
• Summary: Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008]