Human AP1S1 activation kit by CRISPRa

CAT#: GA100837

AP1S1 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 1 subunit sigma 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AP1S1
• Locus ID: 1174
• Kit Components:

  GA100837G1, AP1S1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100837G2, AP1S1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100837G3, AP1S1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001283, NM_057089
• Synonyms: AP19; CLAPS1; EKV3; MEDNIK; SIGMA1A
• Summary: 'The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008]'