Human CLCN2 activation kit by CRISPRa

CAT#: GA100843

CLCN2 CRISPRa kit - CRISPR gene activation of human chloride voltage-gated channel 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLCN2
• Locus ID: 1181
• Kit Components:

  GA100843G1, CLCN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100843G2, CLCN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100843G3, CLCN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171087, NM_001171088, NM_001171089, NM_004366
• Synonyms: CIC-2; clC-2; CLC2; ECA2; ECA3; EGI3; EGI11; EGMA; EJM6; EJM8; LKPAT
• Summary: 'This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]'