Human Clusterin (CLU) activation kit by CRISPRa

CAT#: GA100851

CLU CRISPRa kit - CRISPR gene activation of human clusterin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLU
• Locus ID: 1191
• Kit Components:

  GA100851G1, Clusterin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100851G2, Clusterin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100851G3, Clusterin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171138, NM_001831, NM_203339, NR_038335, NR_045494
• Synonyms: AAG4; APOJ; CLI; KUB1; MGC24903; SGP-2; SGP2; SP-40; TRPM-2; TRPM2
• Summary: 'The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]'