Human CNG1 (CNGA1) activation kit by CRISPRa

CAT#: GA100879

CNGA1 CRISPRa kit - CRISPR gene activation of human cyclic nucleotide gated channel subunit alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CNGA1
• Locus ID: 1259
• Kit Components:

  GA100879G1, CNG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100879G2, CNG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100879G3, CNG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000087, NM_001142564
• Synonyms: CNCG; CNCG1; CNG-1; CNG1; RCNC1; RCNCa; RCNCalpha; RP49
• Summary: 'The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Multiple transcript variants have been found for this gene. [provided by RefSeq, Oct 2019]'