Human Collagen VI (COL6A2) activation kit by CRISPRa

CAT#: GA100906

COL6A2 CRISPRa kit - CRISPR gene activation of human collagen type VI alpha 2 chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COL6A2
• Locus ID: 1292
• Kit Components:

  GA100906G1, Collagen VI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100906G2, Collagen VI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100906G3, Collagen VI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001849, NM_058174, NM_058175
• Synonyms: BTHLM1; PP3610; UCMD1
• Summary: 'This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]'