Human CPT1B activation kit by CRISPRa

CAT#: GA100963

CPT1B CRISPRa kit - CRISPR gene activation of human carnitine palmitoyltransferase 1B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CPT1B
• Locus ID: 1375
• Kit Components:

  GA100963G1, CPT1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100963G2, CPT1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100963G3, CPT1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145134, NM_001145135, NM_001145136, NM_001145137, NM_004377, NM_152245, NM_152246, NM_152247
• Synonyms: CPT1-M; CPT1M; CPTI; CPTI-M; M-CPT1; MCCPT1; MCPT1
• Summary: 'The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]'