Human CD21 (CR2) activation kit by CRISPRa

CAT#: GA100967

CR2 CRISPRa kit - CRISPR gene activation of human complement C3d receptor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CR2
• Locus ID: 1380
• Kit Components:

  GA100967G1, CD21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100967G2, CD21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100967G3, CD21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001006658, NM_001877
• Synonyms: C3DR; CD21; CR; CVID7; SLEB9
• Summary: 'This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]'