Human CK1 epsilon (CSNK1E) activation kit by CRISPRa

CAT#: GA101025

CSNK1E CRISPRa kit - CRISPR gene activation of human casein kinase 1 epsilon

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CSNK1E
• Locus ID: 1454
• Kit Components:

  GA101025G1, CK1 epsilon gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101025G2, CK1 epsilon gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101025G3, CK1 epsilon gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001894, NM_152221
• Synonyms: CKIepsilon; HCKIE
• Summary: 'The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]'