Human Cystatin SN (CST1) activation kit by CRISPRa

CAT#: GA101037

CST1 CRISPRa kit - CRISPR gene activation of human cystatin SN

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CST1
• Locus ID: 1469
• Kit Components:

  GA101037G1, Cystatin SN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101037G2, Cystatin SN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101037G3, Cystatin SN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001898
• Synonyms: cystatin 1; cystatin SA-I; cystatin SN; cysteine proteinase inhibitor, type 2 family; OTTHUMP00000030444; OTTHUMP00000164184
• Summary: 'The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008]'