Human CSTF3 activation kit by CRISPRa

CAT#: GA101047

CSTF3 CRISPRa kit - CRISPR gene activation of human cleavage stimulation factor subunit 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CSTF3
• Locus ID: 1479
• Kit Components:

  GA101047G1, CSTF3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101047G2, CSTF3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101047G3, CSTF3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033505, NM_001033506, NM_001326
• Synonyms: CSTF-77
• Summary: 'The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'