Human CCN2 activation kit by CRISPRa

CAT#: GA101054

CCN2 CRISPRa kit - CRISPR gene activation of human cellular communication network factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCN2
• Locus ID: 1490
• Kit Components:

  GA101054G1, CCN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101054G2, CCN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101054G3, CCN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001901
• Synonyms: CCN2; HCS24; IGFBP8; NOV2
• Summary: 'The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]'