Human CTP synthase (CTPS1) activation kit by CRISPRa

CAT#: GA101063

CTPS1 CRISPRa kit - CRISPR gene activation of human CTP synthase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTPS1
• Locus ID: 1503
• Kit Components:

  GA101063G1, CTP synthase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101063G2, CTP synthase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101063G3, CTP synthase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301237, NM_001905, NR_125440
• Synonyms: CTPS; IMD24
• Summary: 'This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]'