Human CTRB1 activation kit by CRISPRa

CAT#: GA101064

CTRB1 CRISPRa kit - CRISPR gene activation of human chymotrypsinogen B1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTRB1
• Locus ID: 1504
• Kit Components:

  GA101064G1, CTRB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101064G2, CTRB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101064G3, CTRB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329190, NM_001906
• Synonyms: CTRB
• Summary: 'This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This gene is located adjacent to a related chymotrypsinogen gene. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Jul 2016]'