Human Cathepsin G (CTSG) activation kit by CRISPRa

CAT#: GA101069

CTSG CRISPRa kit - CRISPR gene activation of human cathepsin G

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTSG
• Locus ID: 1511
• Kit Components:

  GA101069G1, Cathepsin G gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101069G2, Cathepsin G gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101069G3, Cathepsin G gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001911
• Synonyms: CATG; CG
• Summary: 'The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]'