Human CYBA activation kit by CRISPRa

CAT#: GA101084

CYBA CRISPRa kit - CRISPR gene activation of human cytochrome b-245 alpha chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYBA
• Locus ID: 1535
• Kit Components:

  GA101084G1, CYBA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101084G2, CYBA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101084G3, CYBA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000101
• Synonyms: p22-PHOX
• Summary: 'Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]'