Human CYP2A7 activation kit by CRISPRa

CAT#: GA101094

CYP2A7 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 2 subfamily A member 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP2A7
• Locus ID: 1549
• Kit Components:

  GA101094G1, CYP2A7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101094G2, CYP2A7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101094G3, CYP2A7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000764, NM_030589
• Synonyms: CPA7; CPAD; CYP2A; CYPIIA7; P450-IIA4
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]