Human CYP3A7 activation kit by CRISPRa

CAT#: GA101095

CYP3A7 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 3 subfamily A member 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP3A7
• Locus ID: 1551
• Kit Components:

  GA101095G1, CYP3A7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101095G2, CYP3A7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101095G3, CYP3A7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000765
• Synonyms: CP37; CYPIIIA7; P-450(HFL33); P-450111A7; P450-HFLA
• Summary: 'This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015]'