Human CYP2A13 activation kit by CRISPRa

CAT#: GA101096

CYP2A13 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 2 subfamily A member 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP2A13
• Locus ID: 1553
• Kit Components:

  GA101096G1, CYP2A13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101096G2, CYP2A13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101096G3, CYP2A13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000766
• Synonyms: CPAD; CYP2A; CYPIIA13
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]