Human Cytochrome p450 2J2 (CYP2J2) activation kit by CRISPRa

CAT#: GA101106

CYP2J2 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 2 subfamily J member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP2J2
• Locus ID: 1573
• Kit Components:

  GA101106G1, CYP2J2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101106G2, CYP2J2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101106G3, CYP2J2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000775, NR_134981, NR_134982
• Synonyms: CPJ2
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]