Human CYP4B1 activation kit by CRISPRa

CAT#: GA101110

CYP4B1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 4 subfamily B member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP4B1
• Locus ID: 1580
• Kit Components:

  GA101110G1, CYP4B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101110G2, CYP4B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101110G3, CYP4B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000779, NM_001099772, NM_001319161, NM_001319162, NM_001319163, NR_135003
• Synonyms: CYPIVB1; P-450HP
• Summary: 'This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]'