Human DAB1 activation kit by CRISPRa

CAT#: GA101124

DAB1 CRISPRa kit - CRISPR gene activation of human DAB adaptor protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DAB1
• Locus ID: 1600
• Kit Components:

  GA101124G1, DAB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101124G2, DAB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101124G3, DAB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021080, NM_001353980, NM_001353983, NM_001353985, NM_001353986, NM_001365792, NM_001365793, NM_001365794, NM_001365795
• Synonyms: disabled homolog 1; disabled homolog 1 (Drosophila); OTTHUMP00000010045; OTTHUMP00000011753
• Summary: 'The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]'