Human CD55 activation kit by CRISPRa

CAT#: GA101128

CD55 CRISPRa kit - CRISPR gene activation of human CD55 molecule (Cromer blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD55
• Locus ID: 1604
• Kit Components:

  GA101128G1, CD55 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101128G2, CD55 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101128G3, CD55 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000574, NM_001114752, NM_001300902, NM_001300903, NM_001300904, NR_125349, NM_001114543, NM_001114544
• Synonyms: CR; CROM; DAF; TC
• Summary: 'This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]'