Human DARS1 activation kit by CRISPRa

CAT#: GA101138

DARS CRISPRa kit - CRISPR gene activation of human aspartyl-tRNA synthetase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DARS1
• Locus ID: 1615
• Kit Components:

  GA101138G1, DARS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101138G2, DARS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101138G3, DARS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001293312, NM_001349
• Synonyms: aspRS; HBSL
• Summary: 'This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]'