Human Drebrin (DBN1) activation kit by CRISPRa

CAT#: GA101145

DBN1 CRISPRa kit - CRISPR gene activation of human drebrin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DBN1
• Locus ID: 1627
• Kit Components:

  GA101145G1, Drebrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101145G2, Drebrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101145G3, Drebrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004395, NM_080881, NM_001363541, NM_001364152, NM_001364151
• Synonyms: D0S117E
• Summary: 'The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]'