Human DHPS activation kit by CRISPRa

CAT#: GA101196

DHPS CRISPRa kit - CRISPR gene activation of human deoxyhypusine synthase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DHPS
• Locus ID: 1725
• Kit Components:

  GA101196G1, DHPS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101196G2, DHPS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101196G3, DHPS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206974, NM_001930, NM_013406, NM_013407, NR_038192, NM_001369691, NM_001369693, NR_161467, NR_161469, NM_001369692, NR_161468
• Synonyms: DHS; DS; MIG13
• Summary: 'This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011]'