Human PSD95 (DLG4) activation kit by CRISPRa

CAT#: GA101211

DLG4 CRISPRa kit - CRISPR gene activation of human discs large MAGUK scaffold protein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLG4
• Locus ID: 1742
• Kit Components:

  GA101211G1, PSD95 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101211G2, PSD95 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101211G3, PSD95 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128827, NM_001321074, NM_001321075, NM_001321076, NM_001321077, NM_001365, NR_135527, NM_001369566
• Synonyms: PSD95; SAP-90; SAP90
• Summary: 'This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'