Human DLST activation kit by CRISPRa

CAT#: GA101212

DLST CRISPRa kit - CRISPR gene activation of human dihydrolipoamide S-succinyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLST
• Locus ID: 1743
• Kit Components:

  GA101212G1, DLST gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101212G2, DLST gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101212G3, DLST gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244883, NM_001933, NR_033814, NR_045209
• Synonyms: DLTS
• Summary: 'This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]'