Human DLX4 activation kit by CRISPRa

CAT#: GA101216

DLX4 CRISPRa kit - CRISPR gene activation of human distal-less homeobox 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLX4
• Locus ID: 1748
• Kit Components:

  GA101216G1, DLX4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101216G2, DLX4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101216G3, DLX4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001934, NM_138281
• Synonyms: BP1; DLX7; DLX8; DLX9; OFC15
• Summary: 'Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008]'