Human SARDH activation kit by CRISPRa

CAT#: GA101221

SARDH CRISPRa kit - CRISPR gene activation of human sarcosine dehydrogenase

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Frequently bought together (2)
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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol SARDH
Locus ID 1757
Kit Components

GA101221G1, SARDH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101221G2, SARDH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101221G3, SARDH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001134707, NM_007101
Synonyms BPR-2; DMGDHL1; SAR; SARD; SDH
Summary 'This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.