Human DNAH6 activation kit by CRISPRa

CAT#: GA101229

DNAH6 CRISPRa kit - CRISPR gene activation of human dynein axonemal heavy chain 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAH6
• Locus ID: 1768
• Kit Components:

  GA101229G1, DNAH6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101229G2, DNAH6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101229G3, DNAH6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001370
• Synonyms: Dnahc6; DNHL1; HL-2; HL2
• Summary: 'This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Mutations in this gene may cause primary ciliary dyskinesia (PCD) as well as heterotaxy. [provided by RefSeq, Jun 2016]'