Human DYNC1I2 activation kit by CRISPRa

CAT#: GA101239

DYNC1I2 CRISPRa kit - CRISPR gene activation of human dynein cytoplasmic 1 intermediate chain 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DYNC1I2
• Locus ID: 1781
• Kit Components:

  GA101239G1, DYNC1I2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101239G2, DYNC1I2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101239G3, DYNC1I2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271785, NM_001271786, NM_001271787, NM_001271788, NM_001271789, NM_001271790, NM_001320882, NM_001320883, NM_001320884, NM_001378
• Synonyms: DIC74; DNCI2; IC2
• Summary: 'This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]'