Human Dnmt2 (TRDMT1) activation kit by CRISPRa

CAT#: GA101243

TRDMT1 CRISPRa kit - CRISPR gene activation of human tRNA aspartic acid methyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRDMT1
• Locus ID: 1787
• Kit Components:

  GA101243G1, Dnmt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101243G2, Dnmt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101243G3, Dnmt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004412, NM_176081, NM_176083, NM_176084, NM_176085, NM_176086, NM_001321006, NM_001321007, NM_001351219, NM_001351220, NM_001351221, NM_001351222, NM_001351223
• Synonyms: DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
• Summary: 'This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]'