Human DPEP1 activation kit by CRISPRa

CAT#: GA101253

DPEP1 CRISPRa kit - CRISPR gene activation of human dipeptidase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DPEP1
• Locus ID: 1800
• Kit Components:

  GA101253G1, DPEP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101253G2, DPEP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101253G3, DPEP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128141, NM_004413
• Synonyms: MBD1; MDP; RDP
• Summary: 'The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]'