Human DPP6 activation kit by CRISPRa

CAT#: GA101257

DPP6 CRISPRa kit - CRISPR gene activation of human dipeptidyl peptidase like 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DPP6
• Locus ID: 1804
• Kit Components:

  GA101257G1, DPP6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101257G2, DPP6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101257G3, DPP6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039350, NM_001290252, NM_001290253, NM_001936, NM_130797, NM_001364497, NM_001364499, NM_001364500, NM_001364502, NM_001364498, NM_001364501, NR_157195, NR_157196
• Synonyms: DPL1; DPPX; MRD33; VF2
• Summary: 'This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'