Human Dopamine D2 Receptor (DRD2) activation kit by CRISPRa

CAT#: GA101266

DRD2 CRISPRa kit - CRISPR gene activation of human dopamine receptor D2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DRD2
• Locus ID: 1813
• Kit Components:

  GA101266G1, DRD2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101266G2, DRD2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101266G3, DRD2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000795, NM_016574
• Synonyms: D2DR; D2R
• Summary: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]